Generics

Interchange of Narrow Therapeutic Index (NTI) Drugs

Policy 9912
 

11/01/1999 Introduced
03/01/2004 Reapproved
12/01/2008 Reapproved
02/08/2024 Reapproved

AMCP supports the Food and Drug Administration's (FDA) position that when an FDA-approved and therapeutically equivalent generic drug is selected, patients, physicians, and pharmacists can be assured that they will see the same clinical results and safety profile as with the equivalent brand name product. Therefore, NTI drugs should not be considered as a separate category for purposes of generic substitution. AMCP believes that pharmacists, in consultation with prescribers, should have the right to use their professional judgment and knowledge of the available scientific information in determining when to substitute a generic product.
 

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