Thought Leadership Program

Transforming Evidence into Action

RWE Thought Leadership Image

Advancing the Use of Real-World Evidence in Coverage Decisions


The challenge: Real-World Evidence (RWE) offers critical insights into how treatments perform in everyday care, yet its use in access decisions remains inconsistent. Payers struggle to assess the quality and credibility of RWE due to variations in study design, data sources, and potential bias. As a result, coverage decisions often rely more heavily on clinical trial data, missing opportunities to use real-world insights that could improve treatment decisions, reduce costs, and advance health equity.
The goal: AMCP aims to strengthen confidence in RWE by building standards, frameworks, and shared understanding across the health care system. Through collaboration among payers, researchers, regulators, and manufacturers, AMCP works to clarify RWE’s role alongside clinical trial data, promote consistent evaluation practices, and demonstrate its value in improving guideline alignment, policy decisions, and patient outcomes.
 

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Precison Medicine Thought Leadership Image

Optimizing Biomarker Testing in Oncology


The challenge: Precision medicine has revolutionized oncology, yet biomarker testing—essential for guiding targeted treatments—remains unevenly applied. Despite clear clinical guidelines, many patients miss opportunities for personalized therapy due to inconsistent testing practices. Barriers such as misaligned payer policies, limited awareness of testing’s value, and the absence of payer-focused frameworks hinder broader adoption across health systems.
The goal: AMCP is working to close this gap by aligning managed care strategies with evidence-based guidelines and advancing the integration of biomarker testing in oncology. Through education, real-world evidence generation, and collaboration among payers, providers, and policy leaders, AMCP aims to ensure that every patient receives the right test and the right treatment at the right time.

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Patient Experience Data - Thought Leadership Image

Making Patient Experience Data Matter in Coverage Decisions

The challenge: Although the value of the patient voice in healthcare is widely acknowledged, Patient Experience Data (PED) remains underused in access and coverage decisions. Many payers lack clarity on what PED represents or how to evaluate it alongside clinical and economic data. Misconceptions, limited awareness of FDA guidance, and concerns about bias or feasibility further hinder its integration into formulary and P&T processes, leaving an important perspective out of decision-making.
The goal: AMCP seeks to advance the credible use of PED by clarifying its role, building payer confidence, and developing practical tools for integration. Through collaboration with payers, regulators, manufacturers, and patient organizations, AMCP aims to embed the patient perspective into access decisions—promoting more transparent, equitable, and patient-centered care.

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Noreen Matthews, AMCP Business Consultant

Noreen Matthews
AMCP Business Consultant
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